Validations Queue

108,318 candidate doc → node links pending adjudication. Each was auto-generated by cosine similarity ≥ 0.55 between document and prediction embeddings (bge-base-en-v1.5, 768-dim). Showing page 17 of 44, 100 rows by similarity. Adjudicating updates doc_node_links.reviewed=true with the chosen polarity, writes per-link rows to audit_log, and removes the row from this queue. Phase 4 inference will use confirmed corroborates/contradicts links as Bayesian evidence.

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Confirm or label (corroborates / contradicts) all unreviewed links above a similarity threshold in one transaction. Each affected row writes a per-link audit_log entry. Capped at 1,000 links per call. Use Preview first.

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Bulk action
SimDocSourcePredDomainPrior
0.59
FDA NDA207947: UPTRAVI (SELEXIPAG) — ACTELION
fda
2026-05-23
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA ANDA211020: BUPROPION HYDROCHLORIDE (BUPROPION HYDROCHLORIDE) — GRAVITI PHARMS
fda
2026-05-29
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA208175: PHENTERMINE HYDROCHLORIDE AND TOPIRAMATE (PHENTERMINE HYDROCHLORIDE) — DR REDDYS LABS SA
fda
2026-05-29
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA218096: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — APOTEX
fda
2026-06-03
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA BLA761063: EMGALITY (GALCANEZUMAB-GNLM) — ELI LILLY AND CO
fda
2026-06-05
235_031
Eli Lilly perilously close to $1 trillion market cap at ~$950B.
Alex Wissner-Gross
Markets/Stocks39%
0.59
FDA ANDA219370: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — AUSON
fda
2026-06-09
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA218821: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — CONCORD BIOTECH LTD
fda
2026-06-09
TK13
Biotech/Synbio Safety Event
15%
0.59
FDA ANDA201972: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — AUROLIFE PHARMA LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA203447: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — ANI PHARMS
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA040331: MEPERIDINE HYDROCHLORIDE (MEPERIDINE HYDROCHLORIDE) — EPIC PHARMA LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA201278: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — RHODES PHARMS
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA077723: HYDROCODONE BITARTRATE AND IBUPROFEN (HYDROCODONE BITARTRATE) — STRIDES PHARMA
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA218754: APREPITANT (APREPITANT) — AZURITY
fda
2026-06-16
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA202677: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — ALVOGEN
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA076636: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — ACTAVIS ELIZABETH
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA019892: DILAUDID (HYDROMORPHONE HYDROCHLORIDE) — RHODES PHARMS
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA087463: OXYCET (ACETAMINOPHEN) — SPECGX LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA213414: DAPSONE (DAPSONE) — ALEMBIC
fda
2026-06-25
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA020622: COPAXONE (GLATIRAMER ACETATE) — TEVA PHARMS USA
fda
2026-06-22
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA202160: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — AUROLIFE PHARMA LLC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA217737: IOHEXOL (IOHEXOL) — AMNEAL
fda
2026-06-25
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA075982: TRAMADOL HYDROCHLORIDE (TRAMADOL HYDROCHLORIDE) — PLIVA
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA040777: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — AMNEAL PHARMS
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA208539: TICAGRELOR (TICAGRELOR) — MICRO LABS
fda
2026-04-27
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.59
FDA ANDA079099: LAMOTRIGINE (LAMOTRIGINE) — GLENMARK PHARMS LTD
fda
2026-04-17
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.59
FDA ANDA091427: PAROXETINE HYDROCHLORIDE (PAROXETINE HYDROCHLORIDE) — AUROBINDO PHARMA USA
fda
2026-04-06
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA079162: TOPIRAMATE (TOPIRAMATE) — INVAGEN PHARMS
fda
2026-04-24
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA078257: ONDANSETRON HYDROCHLORIDE (ONDANSETRON HYDROCHLORIDE) — ONESOURCE SPECIALTY
fda
2026-04-15
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA BLA761235: VABYSMO (FARICIMAB-SVOA) — GENENTECH INC
fda
2026-04-09
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA NDA021880: REVLIMID (LENALIDOMIDE) — BRISTOL MYERS SQUIBB
fda
2026-04-27
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.59
FDA ANDA220493: BUPIVACAINE HYDROCHLORIDE (BUPIVACAINE HYDROCHLORIDE) — ANTHEA PHARMA
fda
2026-04-22
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA210480: LENALIDOMIDE (LENALIDOMIDE) — ALVOGEN
fda
2026-04-27
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.59
FDA ANDA091655: ESCITALOPRAM OXALATE (ESCITALOPRAM OXALATE) — MICRO LABS
fda
2026-04-22
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA ANDA216992: DEFLAZACORT (DEFLAZACORT) — UPSHER SMITH LABS
fda
2026-04-09
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA220328: FLUVOXAMINE MALEATE (FLUVOXAMINE MALEATE) — APPCO
fda
2026-04-30
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA204982: PHENTERMINE HYDROCHLORIDE AND TOPIRAMATE (PHENTERMINE HYDROCHLORIDE) — ACTAVIS LABS FL INC
fda
2026-05-01
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA218364: LEVETIRACETAM IN SODIUM CHLORIDE (LEVETIRACETAM) — MYLAN LABS LTD
fda
2026-05-08
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA076228: RISPERIDONE (RISPERIDONE) — HERITAGE PHARMA AVET
fda
2026-05-07
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA BLA761070: FASENRA (BENRALIZUMAB) — ASTRAZENECA AB
fda
2026-05-13
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA BLA761452: IMMGOLIS (GOLIMUMAB-SLDI) — ACCORD BIOPHARMA INC.
fda
2026-05-15
FUT_019
Global market rapidly accelerates bio-industrial circumvention of fractured supply chains 2026-2031: combination of Webb agentic LAMs overseeing vast bio-reactors powered by sub-cent-per-kWh solar energy creates highly-localized completely-autonomous i...
Multi-Forecaster Synthesis
Biotech/Longevity31%
0.59
FDA NDA220711: BEQALZI (SONROTOCLAX) — BEONE MEDICINES USA
fda
2026-05-13
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA NDA219423: WIDAPLIK (AMLODIPINE BESYLATE) — AZURITY
fda
2026-05-28
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA217379: CAVHANZA (NILOTINIB) — FLEX PHARMA
fda
2026-05-29
248_030
FDA will be first government agency forced to get out of the way; government must accelerate regulation speed thousands of times.
Dave Blundin
Geopolitics50%
0.59
FDA BLA761309: COLUMVI (GLOFITAMAB-GXBM) — GENENTECH INC
fda
2026-06-22
IND_012
NVIDIA BioNeMo platform + Evo 2 model fundamentally compresses a century of biology into a decade — Evo 2 achieves 90% accuracy in BRCA1 predictions; AI models will seamlessly transition generated biological designs into practical, synthesized clinical...
Jensen Huang
Biotech/Longevity68%
0.59
FDA NDA021529: IMPLANON (ETONOGESTREL) — ORGANON
fda
2026-05-28
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.59
FDA ANDA211187: MACITENTAN (MACITENTAN) — TEVA PHARMS USA INC
fda
2026-06-08
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA200296: RISEDRONATE SODIUM (RISEDRONATE SODIUM) — AUROBINDO PHARMA LTD
fda
2026-06-08
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.59
FDA ANDA219530: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — MACLEODS PHARMS LTD
fda
2026-06-03
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA212990: LABETALOL HYDROCHLORIDE (LABETALOL HYDROCHLORIDE) — EPIC PHARMA LLC
fda
2026-06-08
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA064050: CLINDAMYCIN PHOSPHATE (CLINDAMYCIN PHOSPHATE) — PADAGIS US
fda
2026-06-10
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA219830: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — ORIENT PHARMA
fda
2026-06-09
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA NDA206321: SAXENDA (LIRAGLUTIDE) — NOVO
fda
2026-06-02
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA203863: HYDROCODONE BITARTRATE AND ACETAMINOPHEN (ACETAMINOPHEN) — EPIC PHARMA LLC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA201194: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — VISTAPHARM LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA204575: HYDROCODONE BITARTRATE AND IBUPROFEN (HYDROCODONE BITARTRATE) — AUROLIFE PHARMA LLC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA077712: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — STRIDES PHARMA INTL
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA210644: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — ABHAI LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA213906: LEVORPHANOL TARTRATE (LEVORPHANOL TARTRATE) — SUN PHARM INDS INC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA213155: LIRAGLUTIDE (LIRAGLUTIDE) — MYLAN INSTITUTIONAL
fda
2026-06-15
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA212436: IBRANCE (PALBOCICLIB) — PFIZER
fda
2026-06-24
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA210732: LEVOMILNACIPRAN HYDROCHLORIDE (LEVOMILNACIPRAN HYDROCHLORIDE) — HIKMA
fda
2026-06-25
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA217281: LENALIDOMIDE (LENALIDOMIDE) — NOVUGEN
fda
2026-04-27
CMQ_026
NVIDIA silicon roadmap: Blackwell (2025) → Vera Rubin (2026) → Vera Rubin Ultra (2027) → Feynman (2028) — annual architectural cadence.
Jensen Huang
Semis83%
0.59
FDA ANDA212414: LENALIDOMIDE (LENALIDOMIDE) — HETERO LABS LTD V
fda
2026-04-27
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA NDA219293: DANZITEN (NILOTINIB TARTRATE) — AZURITY
fda
2026-04-14
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA220264: VERICIGUAT (VERICIGUAT) — CHANGZHOU PHARMACEUTICAL FACTORY
fda
2026-04-08
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA ANDA215759: LENALIDOMIDE (LENALIDOMIDE) — BIOCON PHARMA
fda
2026-04-27
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA ANDA211559: DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE (DAPAGLIFLOZIN) — MACLEODS PHARMS LTD
fda
2026-04-06
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA211579: DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE (DAPAGLIFLOZIN) — LUPIN
fda
2026-04-06
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA217180: JAKAFI XR (RUXOLITINIB PHOSPHATE) — INCYTE CORPORATION
fda
2026-05-01
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.59
FDA BLA761349: COSENTYX (SECUKINUMAB) — NOVARTIS PHARMS CORP
fda
2026-04-17
TK13
Biotech/Synbio Safety Event
15%
0.59
FDA ANDA212336: ANDA212336 ((unspecified)) — DR REDDYS LABS LTD
fda
2026-05-07
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA ANDA216537: CARBIDOPA AND LEVODOPA (CARBIDOPA) — AUROBINDO PHARMA LTD
fda
2026-05-08
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA BLA761449: TYENNE (TOCILIZUMAB-AAZG) — FRESENIUS KABI USA
fda
2026-05-20
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA211026: MACITENTAN (MACITENTAN) — SEASONS BIOTECH
fda
2026-05-19
INF_039
Consumer-facing AI hardware shortages will worsen: high-Unified-Memory Apple Mac Studio lead times now range 6 days to 6 weeks (up to ~54 days) because data centers are absorbing the world's HBM and memory supply — DRAM market transitioning to hourly v...
Alex Finn
Consumer77%
0.59
FDA ANDA217758: AMMONIUM LACTATE (AMMONIUM LACTATE) — ZYDUS LIFESCIENCES
fda
2026-05-15
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA NDA022561: MAVENCLAD (CLADRIBINE) — EMD SERONO INC
fda
2026-05-14
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA BLA022472: AFREZZA (INSULIN RECOMBINANT HUMAN) — MANNKIND
fda
2026-05-29
245_027
Colossal DNA synthesis delivery will reach 20x the largest prior delivery by end of 2026
Ben Lamm
Biotech/Longevity41%
0.59
FDA BLA761069: IMFINZI (DURVALUMAB) — ASTRAZENECA UK LTD
fda
2026-05-28
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.59
FDA ANDA070311: DIAZEPAM (DIAZEPAM) — HIKMA
fda
2026-06-01
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA BLA761061: TREMFYA (GUSELKUMAB) — JANSSEN BIOTECH
fda
2026-05-28
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA209633: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — BRECKENRIDGE
fda
2026-06-03
COD_BIO_002
An AI-designed Isomorphic or peer drug enters or completes Phase 1 by end 2027
Codex Research Pack
Biotech/Longevity50%
0.59
FDA BLA761089: AJOVY (FREMANEZUMAB-VFRM) — TEVA PHARMS USA
fda
2026-06-05
IND_010
Autonomous orbital manufacturing (facilitated by companies like Varda Space Industries) will successfully return pharmaceutical products processed in microgravity that are commercially superior to those manufactured on Earth by 2026 — new Biotech front...
Jared Isaacman
Biotech/Longevity43%
0.59
FDA NDA050671: VANCOMYCIN HYDROCHLORIDE IN PLASTIC CONTAINER (VANCOMYCIN HYDROCHLORIDE) — BAXTER HLTHCARE
fda
2026-06-09
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA212374: EMPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE (EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE) — AUROBINDO PHARMA LIMITED
fda
2026-06-11
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA206321: SAXENDA (LIRAGLUTIDE) — NOVO
fda
2026-06-02
CMQ_010
True AGI requires genuine scientific-discovery capabilities (AlphaFold-class breakthroughs) — brute-force LLM scaling alone is insufficient.
Demis Hassabis
AI49%
0.59
FDA ANDA215230: BRIMONIDINE TARTRATE AND TIMOLOL MALEATE (BRIMONIDINE TARTRATE) — ALEMBIC
fda
2026-06-11
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA209738: TOFACITINIB CITRATE (TOFACITINIB CITRATE) — MICRO LABS
fda
2026-06-03
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.59
FDA ANDA077494: RISPERIDONE (RISPERIDONE) — PH HEALTH
fda
2026-06-08
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA NDA208434: ALECENSA (ALECTINIB HYDROCHLORIDE) — HOFFMANN-LA ROCHE
fda
2026-06-11
INF_027
AI infrastructure applied to structural biology will compress drug-development timelines from approximately a decade to weeks — potentially eradicating many major diseases within 10 years. Requires localized high-speed InfiniBand networking inside the DC.
Demis Hassabis
Biotech/Longevity38%
0.59
FDA BLA761262: SKYRIZI (RISANKIZUMAB-RZAA) — ABBVIE INC
fda
2026-06-26
233_019
Alpha plans to conduct a million-student pharmaceutical-grade randomized control trial on Timeback.
Joe Liemandt
Education35%
0.59
FDA ANDA203823: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — LANNETT CO INC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA204246: FYREMADEL (GANIRELIX ACETATE) — SUN PHARM
fda
2026-06-16
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA202537: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — VISTAPHARM LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA214378: TAPENTADOL HYDROCHLORIDE (TAPENTADOL HYDROCHLORIDE) — EPIC PHARMA LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA211748: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — ALKEM LABS LTD
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA209021: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — ASCENT PHARMS INC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA NDA021011: ROXICODONE (OXYCODONE HYDROCHLORIDE) — SPECGX LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%
0.59
FDA ANDA207418: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — ASCENT PHARMS INC
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA202116: OXYCODONE HYDROCHLORIDE (OXYCODONE HYDROCHLORIDE) — ALVOGEN
fda
2026-06-18
242_048
FDA will move to zero clinical trial model given enough Bayesian/computational evidence
Alex Wissner-Gross
Biotech/Longevity31%
0.59
FDA ANDA040545: OXYCODONE AND ACETAMINOPHEN (ACETAMINOPHEN) — SPECGX LLC
fda
2026-06-18
COD_BIO_001
FDA finalizes or materially advances AI-for-drug-submission guidance by end 2026
Codex Research Pack
Biotech/Longevity47%